Episode 3.2 · 17 min
RNA Before Cells
RNA copying, chemical cycles, metabolism, and dividing compartments illuminate possible routes toward the first cells, along with the gaps experiments have yet to close.
Watch this film on YouTube ↗Visual credits
5 sourcesVisual sources include third-party material incorporated into custom animations. License information is reproduced from source records; an unrecorded license does not mean a work is public domain.
PhilHolliger image
X
View original source ↗License not recordedExpl2282 - Flickr - NOAA Photo Library
IFE, URI-IAO, UW, Lost City Science Party; NOAA/OAR/OER; The Lost City 2005 Expedition.
View original source ↗Public domainChirality with hands
Original: Unknown Vector: -- πϵρ ήλιο
View original source ↗Public domainFigure 2 from Zhu and Szostak, Coupled Growth and Division of Model Protocell Membranes: repeated micelle-fed growth into thread-like vesicles and agitation-driven division, with microscopy insets and a cycle schematic.
Ting F. Zhu and Jack W. Szostak
View original source ↗Copyrighted material — used for documentary commentaryEditorial use; no open license asserted.
Scientific figure · source page 13
Biorxiv
Figure or page excerpt cropped from the source publication.
Research references
Selected sources from the episode’s research and scientific figures.
- 10.1126/science.adt2760 ↗
- 10.1038/s41557-025-01830-y ↗
- 10.1073/pnas.2321592121 ↗
- 10.1371/journal.pcbi.0010061 ↗
- 10.1038/ng1621 ↗
- 10.1073/pnas.50.5.905 ↗
- 10.1073/pnas.58.1.217 ↗
- 10.1038/s41586-022-04676-3 ↗
- 10.1038/s41586-025-09388-y ↗
- 10.1038/s41467-024-52362-x ↗
- 10.1039/D3CS00594A ↗
- 10.1038/s41467-023-36940-z ↗
- 10.1002/syst.202300008 ↗
- 10.1021/jacs.4c08226 ↗
- 10.1039/D2CC03541C ↗
- 10.1021/acs.jpcb.3c05824 ↗
- 10.3390/life12101595 ↗
- 10.1073/pnas.2423683122 ↗
- 10.1073/pnas.2505126122 ↗
- 10.1021/jacs.4c16905 ↗
- 10.1371/journal.pbio.3003155 ↗
Music
- Meditation From The Star Orion
OctahedronMusic · Envato Elements
How this film was made
Created and editorially directed by Anders Lunde using a custom production system developed over six months. AI assists research, drafting, programming, and visual production; I review and edit the material and make the final editorial decisions. Narration uses text-to-speech. Visuals combine custom-built scientific animations, AI-generated reconstructions, and credited scientific imagery.
Generated reconstructions illustrate scientific interpretations. They are distinct from photographs, specimens, and measured data.
More about the creator and production →